PDF; Orai porno: 407
Orai porno: 407
Thiol dependent intramolecular locking of Orai1 channels
Store operated Ca2 entry mediated by STIM1 gated Orai1 channels is essential to activate immune cells and its inhibition or gain of function can lead to immune dysfunction and other pathologies.
STIM1 thermosensitivity defines the optimal preference
Mammals possess a remarkable ability to sense subtle temperature deviations from the thermoneutral skin temperature of ~33 °C, which ensures precise warm sensation. However, the underlying ...
Calcium signaling in immune cells | Nature Immunology
Calcium acts as a second messenger in many cell types, including lymphocytes. Resting lymphocytes maintain a low concentration of Ca2 . However, engagement of antigen receptors induces calcium ...
Polygonum aviculare L extract and quercetin attenuate
Because of the serious side effects of the currently used bronchodilators, new compounds with similar functions must be developed. We screened several herbs and found that Polygonum aviculare L ...
Modulation of intracellular calcium signaling by microRNA
Adjusting intracellular calcium signaling is an important feature in the regulation of immune cell function and survival. Here we show that miR 34a 5p, a small non coding RNA that is deregulated ...
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